Quigley E-250 as a donor for E-350?


I came across an 1997 Quigley E-250 gasser for sale not far from me.. (it's posted in the for sale section)

I have a 1994 E-350 2WD Diesel Ambulance.

Out of curiosity.. would it be feasible to cannibalize the E-250 and convert the E-350 to 4WD?

(yes.. I am aware of Chris and the Ujoint offerings.. )

but.. let's just say in an alternate reality, if I were to price out front axle, transfer case, etc, etc.. and in my dream I lowball the owner and he agrees,
is the parts swap something that is possible without reinventing the wheel or is it too much effort with a load of considerations ?