Yes. I run a bunch of icom gear that is all dstar enabled.
Mostly, it's to eliminate static when we are still en-route. There isn't much interference in the wilderness so audio quality generally isn't an issue while remote.
I don't think I really gain much, but the gps-subdata has been useful a total of two times. It saved us a few minutes of reading the coordinates.
Mostly, I chose this hardware due to icom's gps-aware dr memory that allows you to "find nearby repeaters" from the programmed list of 1500 repeaters, in conjunction with the ability to page in/out pages of 1500 programmed repeaters to/from the built in SD card. This functionality allows me to use "find nearby repeater" anyplace in the western United States with every repeater on repeaterbook programmed in.
I slapped a yaesu ftm400 into my fj a while back, mainly because i just like new stuff (kept the ftm350 as well though) and while i love the radio, there just isnt much fusion activity in my area. More imoortant, i o ly know one person among those i ever travel with that has a fusion capable radio. Kinda a shame since the digital modes, and instant distance/bearing with gps enabled would be really handy.
Picked up some dmr handhelds to tinker with as well but still ran into a lack of people i wanna talk to.
Just not enough market saturation yet. The cost and complexity seems to keep a lotta people away too. Its hard to justify more hardware when you have perfectly good analog fm equipment already in place.