I wear baggies over my padded spandex shorts on longer rides, I used to ride with Fox baggies that had padding built in, that were good also. Lots of areas to fine tune the ride also. Seat up and down, forward and back on the seat rails, and tilt (nose up or flat). I used to get numbness in the hands on longer rides but getting a bar with 15-20 deg sweep and good grips have helped with that. The biggest thing is that your body hardens up. Start slow but make some longer rides you will be sore. If you stick with it you will hurt less and feel stronger. Other things that have helped my wife is getting a Thudbuster seat post. She rode it for a few years and now she does not "require" it like she used to on all her bikes.